Gavi, the Vaccine Alliance, has approved an investment to support the launch, procurement, and delivery of malaria vaccines in Gavi-eligible countries in Sub-Saharan Africa in 2022-2025.

This additional tool in the battle against malaria will be implemented with an initial investment of US$ 155.7 million from 2022 to 2025. The addition of the RTS,S malaria vaccine to presently approved malaria control strategies could assist Africa – the continent with the highest malaria load – reduce infant mortality.

“The Gavi Board’s approval of funding for a new malaria immunization program gives me tremendous hope,” stated José Manuel Barroso, Chair of the Gavi Board. “We are better prepared to confront this devastating illness thanks to the global health community’s combined efforts, and if the vaccine is pushed out at scale, we will be able to help prevent millions of lives.”

Following today’s announcement, a series of important following steps must be completed before the vaccine may be distributed to Gavi-supported nations. This includes technical guidelines on how to use the vaccine in conjunction with other malaria interventions, vaccine procurement, and the opening of the financing window to allow applications from Gavi-supported countries.

The approval of the funding follows WHO’s recommendation for wider routine use of the RTS,S malaria vaccine on 6 October 2021. African countries played a critical role in the positive recommendation, as it was based on data gathered trough the Malaria Vaccine Implementation Programme (MVIP) which took place in Kenya, Ghana and Malawi over a two-year period and a clinical trial around the seasonal delivery of the vaccine in Mali and Burkina Faso. The vaccine received a positive scientific opinion from the European Medicines Agency (EMA) under its article 58 for medicines for use outside of the EU in 2015.

“Ghana, together with several countries on the continent, is proud to have been involved in the pilot program and the development of the first approved malaria vaccine, and today we welcome the decision made by the Gavi board to invest in the malaria vaccine programme. We must now work together to ensure children across the continent can benefit from this additional malaria intervention,” said Hon. Kwaku Agyeman-Manu, Minister of Health of Ghana

Following the WHO’s recommendation for greater routine use of the RTS,S malaria vaccine on October 6, 2021, the money was approved. The good recommendation was based on data acquired through the Malaria Vaccine Implementation Programme (MVIP), which took place over a two-year period in Kenya, Ghana, and Malawi, as well as a clinical trial around the vaccine’s seasonal administration in Mali and Burkina Faso. In 2015, the European Medicines Agency (EMA) gave the vaccine a favourable scientific opinion under its article 58 for medicines used outside the EU.

“Ghana, along with several other African countries, is happy to have participated in the pilot program and creation of the first authorized malaria vaccine, and we applaud the Gavi board’s decision to invest in the malaria vaccine program today.” “Now we must work together to ensure that children across the continent benefit from this additional malaria intervention,” stated Ghana’s Minister of Health, Hon. Kwaku Agyeman-Manu.

The malaria vaccine reached more than two-thirds of the children in the pilot countries who were not in bedsits, demonstrating that child immunization is a powerful platform for reaching vulnerable children, including those who are unreachable with current prevention interventions, and can help advance the equity agenda.

“We are ecstatic to hear of Gavi’s intention to invest in a new malaria-control technology. In regions where it has been utilized in Kenya, the RTS,S vaccine has proven to be a valuable supplement to the already recommended malaria prevention strategies. Dr Rose Jalang’o, National Vaccines and Immunization Program, Ministry of Health of Kenya, said, “We welcome the news of Gavi financing to enable greater use of this vaccine, which has the potential to save tens of thousands of young children’s lives each year on our continent.”

Malaria kills about 260 000 African children under the age of five every year, with six Gavi-eligible countries accounting for half of worldwide mortality.


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